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Butterbur has been used as a herbal remedy at least since the Middle Ages and possibly much earlier. It was used to treat fevers and plague, and as an external poultice on wounds. Later it came to be used as a painkiller for stomach cramps and headaches and to treat chronic coughing and even asthma.

More recent scientific studies suggest that the herb extracts have anti-spasmodic and anti-inflammatory properties. Muscle spasms are associated with stomach cramps, coughs and some types of back pain, as well as migraine and tension headaches. A course of treatment comprising two daily 50mg doses of butterbur extract has been shown to be very effective in reducing the occurrence and severity of attacks in long-term migraine sufferers. Less evidence exists however regarding its effectiveness for other painful conditions, or for asthma.

Butterbur may be a very effective treatment for hay fever. It was recently compared to an antihistamine and did just as well in controlling hay fever symptoms, but did not produce drowsiness. This plant contains substances that are known to affect the immune system, and it has also been used to treat asthma.

A new study, conducted by Swiss researchers, was carried out on 125 hay fever (seasonal allergic rhinitis) sufferers. Over two weeks, the subjects were given either cetirizine (an anti-histamine often used for hay fever treatment) or butterbur extract. Both treatments were shown to be equally effective but the cetirizine patients had more symptoms of drowsiness as a side effect of the drug.

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