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Physiologics - Cinnamon 1000 mg with Chromium Picolinate 60 caps Physiologics - Cinnamon 1000 mg with Chromium Picolinate 60 caps

SKU: PHY-55534    UPC: 716963555340

Suggested Retail Price: $16.39  SRP
 
Our Price: $14.75    Save 10%
  (Total Health web price as of 07/31/14)

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RODUCT IS A SYNERGISTIC MIXTURE OF:
Cinnamon and Chromium Picolinate

PRODUCT DISCUSSION
Cinnamon and Chromium Picolinate are two clinically studied ingredients for support of sugar and fat metabolism.* In a lab study involving 50 different herbs and spices, Cinnamon was found to be the most bioactive ingredient tested.* Chromium is involved with proper receptor functioning necessary for nutrient metabolism.*

STRUCTURE AND FUNCTION
Cinnamon is an ancient herb mentioned in Chinese texts as long ago as 4,000 years, and has an expansive range of historical uses in many different cultures. It contains the important compounds eugenol and cinnamaldehyde, and has been traditionally used for wellness. Cinnamon has been shown to enhance in vitro glucose uptake and glycogen synthesis and to increase phosphorylation of the insulin receptor; moreover, cinnamon extracts are likely to aid in triggering the insulin cascade system.*

Research indicates that as a supplement, Cinnamon helps support sugar and fat metabolism in the body.* It also helps to maintain a healthy metabolism of nutrients, making it an excellent choice for an herbal addition to your health program.*

Chromium is an essential trace element essential to humans for proper carbohydrate and lipid metabolism.* Chromium exists in several valence states, of which the trivalent (III) and hexavalent states are the most common. Most chromium in the food supply is in the trivalent state. Chromium picolinate consists of organic trivalent chromium and picolinic acid, a natural derivative of tryptophan.

A naturally-occurring oligopeptide, low-molecularweight Chromium-binding substance (LMWCr), binds four Chromium ions and is capable of binding to sugar metabolism receptors, promoting receptor kinase activity. It acts in a similar manner as Calmodulin does with Calcium, and hence is named Chromodulin.* Chromium is also part of the Glucose Tolerance Factor, composed of chromic ion, nicotinic acid, and amino acids glycine, glutamic acid and cysteine.*

INDICATIONS
Glucose metabolism can be a concern for people of all ages and ethnic backgrounds. In baked goods, levels of cinnamon can range from 1.3-1.4%. In contrast, our Cinnamon supplement provides 1000 mg of Cinnamon per capsule, and 1 gram of Cinnamon per daily serving. Taking advantage of the benefits of Cinnamon in supplement form may be a more practical choice than just relying on the small amounts you may eat in foods.

The National Research Council estimates that chromium intake in the U.S. is 25-33 mcg/day, with more than 90% of persons having a suboptimal daily intake of less than 50mcg/day. Supplementing with chromium in an absorbable complex with picolinic acid is an easy and affordable way to support the metabolism of glucose and other dietary macronutrients.*

HOW CLIENTS MAY BENEFIT
  • Helping to ensure an adequate daily Chromium and Cinnamon intake which may be at sub-optimal levels in many individuals.
  • By supporting sugar, fat and protein metabolism all in one convenient supplement.*
  • Using a dietary supplement with ingredients backed by scientific research and testing.
  • Suitable for a wide-range of clients due to its free of status for yeast, wheat, milk or milk derivatives, lactose, sugar, preservatives, soy, sodium (less than 5mg per serving), and artificial color and flavor as certified through analysis of raw material specification sheets.

CLINICAL EVIDENCE
  • In a randomized placebo-controlled, clinical trial, 60 men and women were given 1, 3, or 6 g of cinnamon daily or matching placebo for 40 days. After 40 days, those in the cinnamon group had significantly improved scores in glucose, triglyceride, and cholesterol metabolic parameters. There were no changes seen in the placebo group. This trial demonstrated that all three doses of cinnamon effectively supported sugar and fat metabolism, which can have implications in heart health.
  • 50 subjects were studied in a double-blind, placebo controlled, crossover fashion to determine the metabolic interaction of Chromium and carbohydrates. Chromium supplementation markedly elevated serum Chromium levels and promoted sugar metabolism at a Pvalue of .001. (Ghosh/02)
SUMMARY
Research indicates that as a supplement, Cinnamon helps support sugar and fat metabolism in the body.* It also helps to maintain a healthy metabolism of nutrients, making it an excellent choice for an herbal addition to your health program.* Chromium, in the clinically-studied and absorbable from of chromium picolinate, is recommended for anyone looking to support glucose metabolism and the metabolism of other dietary macronutrients. One tablet can be taken daily to help promote sugar and fat metabolism.* Physiologics offers a high-quality formula that is free of milk and soy allergens and dosed at levels consistent with published, clinical research.*

SUGGESTED DOSAGE
For adults, take one (1) capsule daily, preferably with a meal or follow the advice of your health care professional. Capsules can be opened and the contents added to your favorite beverage or food. As a reminder, discuss the supplements and medications you take with your health care providers.

REFERENCES
Prevalence of total diabetes in the United States, all ages - United States, 2002. http://www.diabetes.org/diabetes-statistics/national-diabetes-fact-sheet.jsp

Agricultural Research Service. Dr. Duke's Phytochemical and Ethnobotanical Databases. Available at: www.arsgrin.gov/duke/.

Onderoglu S, Sozer S, Erbil KM, et al. The evaluation of long-term effects of cinnamon bark and olive leaf on toxicity induced by streptozotocin administration to rats. J Pharm Pharmacol 1999;51:1305-12.

Lee, NA. et al. Beneficial effect of chromium supplementation on serum triglyceride levels in NIDDM. Diabetes Care. 1994, 17(12); Dec: 1449-1452.

Press, R.I., et al. The effect of chromium picolinate on serum cholesterol and apolipoprotein fractions in human subjects. West J Med. 1990. 152:41-45

Ghosh, D., et al. Role of chromium supplementation in Indians with type 2 diabetes mellitus. J Nutr Biochem. 2002. 13(11); Nov: 690-697.

Anderson RA, Broadhurst CL, Polansky MM, et al. Isolation and Characterization of Polyphenol Type-A Polymers from Cinnamon with Insulin-like Biological Activity. J Agric Food Chem 2004;52:65-70.

Jarvill-Taylor KJ, Anderson RA, Graves DJ. A hydroxychalcone derived from cinnamon functions as a mimetic for insulin in 3T3-L1 adipocytes. J Am Coll Nutr 2001;20:327-36.

Lamson D.S. & Plaza S.M. (2002) The safety and efficacy of high-dose chromium. Altern Med Rev. 7(3):218-35.

Lee, N.A. & Reasner, C.A. (1994) Beneficial effect of chromium supplementation on serum triglyceride levels in NIDDM. Diabetes Care. 17(12):1449-52.

Morris, B.W. et al. (1993) The inter-relationship between insulin and chromium in hyperinsulinaemic euglycaemic clamps in healthy volunteers. J Endocrinol. 139(2):339-45.

Morris, B.W. et al. (1998) Enhancement in insulin sensitivity in healthy volunteers following supplementation with chromium picolinate. Med Biochem. 1:65-72.

Morris, B.W. et al. (1999) Chromium homeostasis in patients with type II (NIDDM) diabetes. J Trace Elem Med Biol. 13(1-2):57-61.

Press, R.I

The statements included above have not been evaluated by the FDA or Total Health. This product is not intended to diagnose, treat, cure or prevent any disease.

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