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Physiologics - DIM Bioavailable Diindolylmethane - 120 Caps Physiologics - DIM Bioavailable Diindolylmethane - 120 Caps

SKU: PHY-50284    UPC: 716963502849

Suggested Retail Price: $57.69  SRP
Our Price: $51.92    Save 10%
  (Web price as of 02/10/16...not applicable to in-store purchases)

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Product Review: Write your own review
Bioavailable Diindolylmethane 120 Capsules Promotes Healthy Estrogen Metabolism*

Patented formulation designed to promote healthy estrogen metabolism* *
Stabilized, bioavailable form of Diindolylmethane (DIM®) PRODUCT DISCUSSION PhysioLogics DIM (bioavailable 3,3-Diindolylmethane) is a patented, stabilized formula that helps promote cellular health and supports the enzymatic basis of healthy estrogen metabolism.*

PRODUCT BENEFITS: As an Indole, diindolylmethane is a natural
constituent of plants, particularly cruciferous vegetables. This
bioavailable, patented form promotes healthy estrogen metabolism
for women and cellular health.*

The compound 3,3-Diindolylmethane is a dietary indole which occurs naturally in Brassica vegetables.
Brassica vegetables are also known as cruciferous vegetables and include broccoli, cauliflower, cabbage, turnips, kale and brussels sprouts.
These vegetables are considered by many scientists to be among the most metabolically healthful foods because of their unique profile of naturally occurring biochemicals. Diindolylmethane is a stable dimer (double molecule) of indole-3-carbinol (I3C), which is generated upon hydrolysis of glucobrassicin, the indole glucosinolate in Brassica vegetables. Dehydration of I3C results in a mixture of oligomeric products, including diindolylmethane.
Diindolylmethane has been shown to have beneficial enzymatic interactions in vitro, which is believed to help mediate its positive effects on estrogen metabolism.* CLINICAL EVIDENCE *
A randomized, double-blind, placebo controlled, clinical study analyzed healthy estrogen metabolism in 20 postmenopausal women. Subjects were given either 108 mg/day of Diindolylmethane as DIM® or a placebo. DIM® treated subjects showed a significant increase in levels of 2-hydroxyestrone (p=0.020) and diindolylmethane (p=0.045), and an increase of 47% in the 2-hydroxyestrone/16-alpha hydroxyestrone ratio (p=0.059).
Based on these results, the authors concluded that DIM® had positive effects on estrogen metabolite ratios. (Dalessandri et al, 2004) *

In a double-blind, placebo-controlled, crossover study, 33 subjects received 60 mg of DIM® or placebo per day in four divided doses. Each study period lasted three months. At three months, a significant positive effect was observed on estrogen metabolism in the treatment group.
No significant effect was observed in the placebo group. (Zeligs et al, 2005)

PhysioLogics DIM® utilizes BioResponse-DIM®, a bioavailable form of Diindolylmethane, that helps promote healthy estrogen metabolism and cellular health.*

SUGGESTED DOSAGE: For adults, take one (1) capsule with a meal up to three times daily or follow the advice of your health care professional. DIM® and BioResponse-DIM® are trademarks of BioResponse.
Supplement Facts
Serving Size 1 Capsule
Amount Per Serving %Daily Value
DIM® blend complex 100 mg **
(Providing 25 mg of Diindolylmethane)
**Daily Value not established.
Other Ingredients: Rice Powder, Gelatin, Silica, Vegetable Magnesium Stearate.
Contains soy ingredients.
FREE OF: yeast, wheat, milk or milk derivatives, lactose, sugar, preservatives,
artificial color, artificial flavor, sodium (less than 5 mg per serving).

TAMPER RESISTANT: Do not use if seal under cap is broken or missing.
Store in a dry place and avoid excessive heat.

Warning: Not intended for use by pregnant or nursing women. If you
are taking any medications, consult your doctor before use. Discontinue
use and consult your doctor if any adverse reactions occur.

The statements included above have not been evaluated by the FDA or Total Health. This product is not intended to diagnose, treat, cure or prevent any disease.

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