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Physiologics - Flush Free Niacin 500 mg  90 caps Physiologics - Flush Free Niacin 500 mg 90 caps

SKU: PHY-55256    UPC: 716963552561

Suggested Retail Price: $15.35  SRP
 
Our Price: $13.81    Save 10%
  (Total Health web price as of 12/28/14)

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  • Helps support overall cardiovascular health*
PRODUCT DISCUSSION
Niacin is a water-soluble B vitamin that plays a role in numerous metabolic reactions in the body, including those that form the coenzymes NAD and NADP. PhysioLogics Flush Free Niacin provides this B-vitamin in a complex with Inositol, a nutrient that is considered a part of the B complex. This formula is flush free, which means that it does not cause an uncomfortable "flush".***

STRUCTURE AND FUNCTION
Each of the B Vitamins plays a unique role in maintaining proper metabolic functioning. Most of the energy in our body is derived from oxidation-reduction (redox) reactions, which are processes involving the transfer of electrons. About 200 enzymes in the body require the niacin coenzymes, NAD and NADP, primarily to accept or donate electrons for redox reactions. Niacin functions in the body as a coenzyme in the metabolism of carbohydrates and proteins. Niacin also helps in the maintenance of cardiovascular health, nervous system and digestive health.*

CLINICAL EVIDENCE
  • In a double-blind, placebo-controlled study, 45 subjects received either 1000 mg of niacin per day or placebo for 1 year. At 52 weeks, cardiovascular function had significantly improved in the active treatment group; no significant effect on the placebo group was observed. Physiologics Flush Free Niacin provides 400mg niacin per day. (Thoenes et al, 2007)
  • A total of 32 subjects completed an observational study in which they received escalating doses of niacin for up to 44 weeks. The subject began the trial with 500 mg/day and periodically increased dosage up to 2000 mg/day. The results indicated significant positive effects on cardiovascular functioning. (Dubè et al, 2006)
SUMMARY
PhysioLogics Flush Free Niacin delivers this important B vitamin for support of cardiovascular health.*

SUGGESTED DOSAGE
For adults, take one (1) capsule daily, preferably with a meal, or follow the advice of a health care professional. Do not exceed one capsule per day.

***NOTICE: Most people should not experience flushing when using this product. However, a few sensitive individuals may experience some flushing. Do not take on an empty stomach.

REFERENCES
Dubè MP, Wu JW, Aberg JA, et al. Safety and efficacy of extended-release niacin for the treatment of dylipidemia in patients with human immunodeficiency virus infection: AIDS clinical trials group study A5148. Antiviral Ther. 2006;11:1081-9.

Kamanna VS, Kashyap ML. Mechanism of action of niacin. Am J Cardiol. 2008;101:20B-26B.

Thoenes M, Oguchi A, Nagamia S, et al. The effects of extended-release niacin on carotid intimal media thickness, endothelial function and inflammatory markers in patients with the metabolic syndrome. Int J Clin Pract. 2007;61:1942-8.

The statements included above have not been evaluated by the FDA or Total Health. This product is not intended to diagnose, treat, cure or prevent any disease.


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