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PRODUCT DISCUSSION
Milk Thistle Extract contains a group of beneficial flavonoids collectively called Silymarin. PhysioLogics Milk Thistle Extract 250 mg has been standardized to contain 80% Silymarin, to help support liver health.* STRUCTURE AND FUNCTION
Free radicals can contribute to oxidative stress, which in turn may contribute to the premature aging of cells. The flavonoids and antioxidants in Milk Thistle Extract promote the action of nucleolar polymerase A, for increased ribosomal protein synthesis.* This promotes healthy liver function and helps support the outer cell membrane structure of hepatocytes.* CLINICAL EVIDENCE - Seventeen subjects who received 160 mg of silymarin three times per week were compared to a control group who received no treatment for four weeks. The subjects who received silymarin experienced a significant improvement in liver function compared with the control group. (Torres et al, 2004)
- Forty nine subjects received either 150 mg of silymarin three times per day, or placebo, for six months. Those receiving silymarin experienced a significant increase in plasma glutathione and antioxidant activity compared with placebo. (Lucena et al, 2002)
SUMMARY
PhysioLogics Milk Thistle Extract contains beneficial flavonoids that promote healthy liver function.* SUGGESTED DOSAGE
For adults, take one (1) capsule three times daily, preferably with meals or follow the advice of a health care professional. Capsules may be opened and prepared as a tea. REFERENCES
Lucena MI, Andrade RJ, de la Cruz JP, et al. Effects of silymarin MZ-80 on oxidative stress in patients with alcoholic cirrhosis. Results of a randomized, double-blind, placebo-controlled clinical study. Int J Clin Pharmacol Ther. 2002;40:2-8. Torres M, Rodríguez-Serrano F, Rosario DJ, et al. Does Silybum Marianum play a role in the treatment of chronic hepatitis C? PR Health Sci J. 2004;23:69-74.
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