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Physiologics - B-Complex Sublingual with B-12  2 oz liquid Physiologics - B-Complex Sublingual with B-12 2 oz liquid

SKU: PHY-55264    UPC: 716963552646

Suggested Retail Price: $9.99  SRP
Our Price: $8.99    Save 10%
  (Web price as of 11/28/15...not applicable to in-store purchases)

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PhysioLogics B-Complex Sublingual Liquid is a multifunctional blend of important B Vitamins, including B-2, B-6, B- 12, Niacin, and Pantothenic Acid. B Vitamins are essential for normal formation of blood cells, and also support a healthy nervous system, energy metabolism, and vision health.* The body requires a daily source of B Vitamins because B Vitamins are water-soluble.

Acid reflux/heartburn medications (proton pump inhibitors) may decrease Vitamin B-12 absorption from the digestive tract. Therefore it can be important to supplement with Vitamin B-12 when using these medications. Note: Vitamin B-12 supplements are not intended to serve as a replacement for Acid Reflux Medications, nor should patients discontinue prescribed medications while supplementing with Vitamin B-12.

Riboflavin (B-2) assists in oxidation/reduction reactions, including those involved in energy pathways and the metabolism of carbohydrates, fats and proteins.* It is also significant for the maintenance of the skin and mucous membranes, the cornea of the eye, and nerve sheaths.*

Niacin (B-3), also known as nicotinic acid and nicotinamide, serves as a coenzyme in oxidation/reduction reactions as nicotinamide adenine dinucleotide (NAD) and its phosphate form (NADP). NAD functions in intracellular respiration and oxidation of glyceraldehydes, lactate, alcohol, and other fuel molecules. NADP is required in reductive biosyntheses, such as fatty acid and steroid synthesis. Niacin is needed for the metabolism of food, maintenance of healthy skin and nerve cells, DNA replication and repair, and cell differentiation.*

The major coenzyme forms of Vitamin B-6, Pyridoxine (B- 6), pyridoxal 5'-phosphate (PLP) and pyridoxamine (PMP), function in the catabolism of carbohydrates, proteins and fats. PLP serves as a coenzyme for more than 100 enzymes involved in amino acid metabolism, including aminotransferases, decarboxylases, and dehydratases. Vitamin B-6 is also used in the production of red blood cells, and is involved in the single-carbon cycle, which produces methyl groups used in the synthesis of other compounds. Vitamin B-12 (Cobalamin) is a coenzyme in the single-carbon cycle, and, with Vitamin B-6 and Folate, converts homocysteine to methionine. Vitamin B-12 is also required for maintenance of nerve sheaths, normal blood formation, and DNA synthesis and repair.*

Pantothenic acid is used for the synthesis of coenzyme A and thus is involved in many metabolic pathways, including energy metabolism; catabolism of carbohydrates, lipids, amino acids; and synthesis of hormones and neurotransmitters.*

  • A review in the Journal of the American Medical Association stated that most people do not consume optimal amounts of vitamins by diet alone. In fact, suboptimal intake of some vitamins, even above levels classified as deficiency, may be unhealthy and is common in the general population. The reviewers concluded that it is wise for all adults to take vitamin supplements. (Fairfield and Fletcher, 2002)
  • The Oxford Healthy Aging Projects, a cohort study conducted from 1993 to 2003, examined the relationship between serum vitamin B-12 status and cognitive function in older adults. A significant association was found between low levels of vitamin B-12 and the incidence and rate of cognitive decline over the ten year period. (Clarke et al, 2007)
The B Vitamins work individually and synergistically in a wide array of biological functions to maintain health.* PhysioLogics B-Complex Sublingual Liquid provides a convenient, easy-to-use, liquid form of high-potency B- Complex vitamins.

SHAKE WELL before use. For adults, place one full dropper (1 mL) under the tongue and hold for 30 seconds before swallowing, or follow the advice of a health care professional.

Aisen PS, Egelko S, Andrews H, et al. A pilot study of vitamins to lower plasma homocysteine levels in Alzheimer disease. Am J Geriatr Psychiatry. 2003;11:246-9.

Centers for Disease Control and Prevention. Recommendations for the use of folic acid to reduce the number of cases of spina bifida and other neural tube defects. MMWR. 1992;41 (No. RR-14).

Clarke R, Birks J, Nexo E, et al. Low vitamin B-12 status and risk of cognitive decline in older adults. Am J Clin Nutr. 2007;86:1384-91.

Fairfield KM, Fletcher RH. Vitamins for chronic disease prevention in adults: scientific review. JAMA. 2002;287:3116-26.

Institute of Medicine. Dietary Reference Intakes: Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline. Washington, DC: National Academy Press, 1998.

Manore MM. Effect of physical activity on thiamine, riboflavin, and vitamin B-6 requirements. Am J Clin Nutr. 2000;72(2 Suppl):598S-606S.

Nilsson K, Warkentin S, Hultberg B, et al. Treatment of cobalamin deficiency in dementia, evaluated clinically and with cerebral blood flow measurements. Aging (Milano). 2000;12:199-207.

Stampfer MJ, Malinow MR, Willett WC, et al. A prospective study of plasma homocysteine and risk of myocardial infarction in US physicians. JAMA. 1992;268:877-81.

Wang HX, Wahlin A, Basun H, et al. Vitamin B(12) and folate in relation to the development of Alzheimer's disease. Neurology. 2001;56:1188-9.

The statements included above have not been evaluated by the FDA or Total Health. This product is not intended to diagnose, treat, cure or prevent any disease.

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