Glucosamine + MSM Forte capsules provided byDouglas Laboratories contain 500 mg of pureglucosamine sulfate and 250 mg ofmethylsulfonylmethane (MSM). Ascorbic acid,proanthocyanidins, and bromelain are also includedto provide additional aid in maintaining the health ofaging joints.
Glucosamine is a naturally occurring amino sugarfound in glycosoaminoglycans, integral componentsof the proteoglycans found in joint cartilage.Proteoglycans are large carbohydrate rich structuresthat provide resiliency, load distribution, shockabsorbing,compressive and lubricating properties tojoints and connective tissues. The availability ofglucosamine is an integral part of the synthesis ofglycosaminoglycans and proteoglycans that arenecessary during the constant remodeling that agingcartilage undergoes. Thus, the maintenance ofhealthy aging cartilage may be improved withenhanced deposition of glycosaminoglycans andproteoglycans.Dietary glucosamine serves as an immediateprecursor for glycosaminoglycan synthesis, and alsostimulates incorporation of other precursors into theconnective tissue matrix. Bioavailability of oralglucosamine sulfate is excellent. It is absorbedintact, and utilized very quickly by all tissues,including connective tissues. Glucosamine sulfate ismore efficiently used for connective tissuemetabolism than other glucosamine sources, such ascartilage extracts or chondroitin sulfate. In summary,glucosamine sulfate is a well recognized, highlyeffective source of glucosamine forglycosaminoglycan and proteoglycan synthesis in allconnective tissues, such as cartilage, ligaments,tendons, skin, and bone.MSM, a derivative of DMSO, is a naturallyoccurring compound of biologically available sulfur,an indispensable element in human nutrition. As partof the amino acids methionine and cysteine, sulfur isrequired for the structural integrity and function ofalmost every protein in the body, as well as theglycosaminoglycans of cartilage and other connectivetissue. Dietary MSM serves as a versatile donor ofmetabolically active sulfur for the synthesis ofnumerous organosulfur compounds and proteins inthe body. As such, MSM helps maintain normalimmune response, lung function, connective tissuemetabolism, and muscle contraction. MSM occursnaturally in a variety of foods, such as fruits,vegetables, cereal grains, milk, and fish. However,MSM is volatile and easily lost during cooking.MSM is very well absorbed by the intestinal tractand rapidly distributed within the body.Bromelain, a protease from the pineapple plant,reduces the production of proinflammatoryprostaglandins by modulating the arachidonatecascade. Its ability to modulate the bodys normalinflammatory processes may reduce the discomfortassociated with aging joints.Proanthocyanidins, such as those found in red wine,are natural polyphenolic bioflavonoids that arewidespread in nature and highly regarded for theirstrong antioxidant properties, as well as theirfunctions in supporting the bodys connective tissues.They have been shown to bind with collagen fibers,thereby protecting from premature degradation. Thishelps maintain the natural elasticity of collagen inskin, joints, arteries, capillaries, and other connectivetissues.Although vitamin C has numerous biologicalfunctions, foremost, it is essential for the synthesis ofcollagen and glycosaminoglycan which are thebuilding materials of all connective tissues, such asjoint cartilage, tendons, blood vessels, skin, and bone.Ascorbic acid (vitamin C) is the required coenzymefor two groups of enzymes that catalyze the crosslinking of collagen fibers -lysyl hydroxylases andprolyl hydroxylases. Consequently, vitamin C isessential for the normal structure and function ofconnective tissue.
Glucosamine + MSM Forte capsules may be auseful nutritional adjunct for individuals who wish tosupport the structure and function of the bodysconnective tissues, such as cartilage, bone, tendons,ligaments, and skin.
Each capsule contains:
Vitamin C (Ascorbic Acid)............................50 mg
Glucosamine Sulfate....................................500 mg
Methylsulfonylmethane (MSM) ...............250 mg
Proanthocyanidins (red wine) ........................10 mg
Bromelain ......................................................10 mg
One capsule per day or as directed by a physician.
Store in a cool, dry place, away from direct light.Keep out of reach of children.
The statements included above have not been evaluated by the FDA or Total Health. This product is not intended to diagnose, treat, cure or prevent any disease.