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Physiologics - Cartilage Companion Plus 60 sgels Physiologics - Cartilage Companion Plus 60 sgels

SKU: PHY-55224    UPC: 716963552240

Suggested Retail Price: $25.65  SRP
Our Price: $23.08    Save 10%
  (Web price as of 11/30/15...not applicable to in-store purchases)

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Glucosamine Sulfate, Chondroitin Sulfate, MSM (Methylsulfonylmethane), Vitamin C (Ascorbic Acid), Vitamin E (d-Alpha Tocopheryl Acetate), Manganese (Manganese Aspartate), Evening Primrose Oil, Flaxseed Oil, Fish Oil

Cartilage Companion® + from PhysioLogics contains the three most popular supplements to support joint health, plus essential and non-essential polyunsaturated Omega fatty acids. Glucosamine and Chondroitin Sulfate are key structural components of cartilage and play a role in the maintenance of joints. MSM is an organic source of sulfur, one of the major building blocks of glucosaminoglycans.*

Cartilage is associated with an extracellular matrix composed of glycosaminoglycans (GAGs) and proteoglycans, which interact with collagen and elastic fibers to cushion joints and provide range of motion. GAGs are long, unbranched polysaccharide chains composed of repeating disaccharide units. Proteoglycans are proteins that carry one or more GAG side chains, and help bind components of cartilage together.

Glucosamine, a key component of cartilage, is an aminomonosaccharide utilized in the synthesis of GAGs and proteoglycans. Glucosamine from food and supplements is incorporated into the metabolic pathway of proteoglycan and GAG synthesis, promoting cartilage production and articular function.*

Chondroitin is also a natural constituent of cartilage, made up of repeating chains of GAGs. By promoting water retention, proteoglycan and GAG synthesis, and healthy enzymatic metabolism of cartilage, Chondroitin supports joint flexibility and function.*

MSM supplies an organic source of sulfur. Sulfur is used in the body as a constituent of certain amino acids, collagen and disulfide bonds, and provides a raw material for the production of GAGs and collagen, making MSM an important part of cartilage and joint maintenance.*

For your clients who are weekend athletes or maturing adults, Cartilage Companion® + provides Glucosamine, Chondroitin and MSM, the three leading ingredients to support joint and cartilage maintenance and promote range of motion. This product also provides all three Omega polyunsaturated fatty acids for additional health benefits.*

  • Supports cartilage maintenance.*
  • Promotes range of motion.*
  • Glucosamine and Chondroitin Sulfate supply natural components of cartilage.*
  • Glucosamine and Chondroitin Sulfate promote proteoglycan and GAG synthesis.*
  • Chondroitin promotes water retention and healthy enzymatic metabolism of cartilage.*
  • MSM provides sulfur, a raw material for GAG and collagen synthesis.*


  • The Lancet published a double-blind placebo-controlled study that investigated the long-term effects of Glucosamine sulphate in a trial of 212 subjects. After 3 years of 1500 mg/day, the subjects that received Glucosamine maintained cartilage as measured in the knee. Joint support was not observed in the placebo group.
  • Another double-blind study observed that subjects given 1500 mg Glucosamine sulfate per day experienced 50% more joint support after 3 weeks and 72% more support after 30 days, while those with placebo reported only 36% more joint support after 30 days.


Cartilage Companion® + provides the three leading ingredients to support joint and cartilage health. Glucosamine and Chondroitin Sulfate are key structural components of cartilage and play an important role in the maintenance of joint cartilage. MSM provides an organic source of sulfur, one of the raw materials of GAGs and collagen. These ingredients work synergistically to support joint health and promote range of motion. In addition, this product provides a source of Omega-3, Omega-6, and Omega-9 polyunsaturated fatty acids.*

For adults, take one (1) softgel three times daily, preferably with a meal or follow the advice of your health care professional. As a reminder, discuss the supplements and medications you take with your health care providers.

Barclay, T.S. et al. Glucosamine. The Annals of Pharmacotherapy. 1998. 32(5); May: 574-579.

De Camara, C.C., et al. Glucosamine sulfate for osteoarthritis. Annals of Pharmacotherapy. 1998.

Deal, CL. et al. Nutraceuticals as therapeutic agents in osteoarthritis; The role of Glucosamine, Chondroitin Sulfate, and Collagen Hydrolysate. Rheum Dis Clin North Am. 1999. 25(2); May: 379-395.

Drovanti, A. et al. Therapeutic activity of oral glucosamine sulfate in osteoarthrosis: A placebo-controlled double-blind investigation. Clinical Therapeutics. 1980. 3: 260-272.

Reginster, J.Y. et al. Long-term effects of glucosamine sulphate on osteoarthritis progression: a randomised, placebo-controlled clinical trial. The Lancet. 2001. 357(9); Jan 27: 251-256.

Sizer, F. et al. Water and minerals: chloride and sulfur. Nutrition: Concepts and Controversies. 7th ed. 1997. Wadsworth Publishing Co. Albany, NY. 303.

The statements included above have not been evaluated by the FDA or Total Health. This product is not intended to diagnose, treat, cure or prevent any disease.

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